Question 1

Which of the following conditions is characterized by a defect of a DNA repair enzyme?

Accepted Answer

A)   Neurofibromatosis
B)   Hereditary polyposis coli
C)   Xeroderma pigmentosum
D)   Wilms' tumor
E)   Hodgkin's lymphomaF) A) and C)
G) B) and C)

Question 2

Researchers who deal with neoplasia in the human populations and also study the environmental causes of tumors are known as:

Accepted Answer

A)   Clinical oncologists
B)   Experimental oncologists
C)   Cancer oncologists
D)   Cancer epidemiologists
E)   Clinical epidemiologistsF) A) and C)
G) All of the above

Question 3

The most important risk factor(s) for breast and colon cancer is (are) :

Accepted Answer

A)   Hormonal imbalance and advanced age
B)   Smoking and promiscuity
C)   Sun exposure and family history
D)   Smoking
E)   Family history of cancer in those locationsF) B) and E)
G) A) and E)

Question 4

Alpha-fetoprotein is a tumor marker for malignant tumors originating in the:

Accepted Answer

A)   Brain
B)   Lung
C)   Liver
D)   Uterus
E)   ThyroidF) B) and C)
G) B) and E) C

Question 5

Benign protuberant tumors found on the skin,mouth,or larynx are called:

Accepted Answer

A)   Tubular adenomas
B)   Villous adenomas
C)   Polyps
D)   Papillomas
E)   CystadenomasF) None of the above
G) D) and E)

Question 6

A lung tumor that has spread to the brain has metastasized via:

Accepted Answer

A)   Lymphatics
B)   Nerves
C)   Blood vessels
D)   Cerebrospinal fluid
E)   Pleural fluidF) B) and C)
G) A) and E)

Question 7

Malignant tumors composed of embryonic cells are often called:

Accepted Answer

A)   Malignant islet cell tumors
B)   Gliomas
C)   Lymphomas
D)   Blastomas
E)   TeratomasF) D) and E)
G) B) and E)

Question 8

The cancer of chimney sweeps identified in the eighteenth century in England was related to a component of tar that is chemically classified as:

Accepted Answer

A)   Polycyclic hydrocarbons
B)   Aflatoxin B1
C)   Azo-dyes
D)   Naphthylamine
E)   ArsenicF) B) and E)
G) A) and E)

Question 9

The incidence of which cancer has been rising in the United States during the past 20 years?

Accepted Answer

A)   Carcinoma of the lung
B)   Carcinoma of the liver
C)   Carcinoma of the stomach
D)   Carcinoma of the thyroid
E)   Malignant brain tumorsF) B) and D)
G) A) and C)

Question 10

Human papillomavirus (HPV) has been implicated in the pathogenesis of carcinoma of the:

Accepted Answer

A)   Lips
B)   Cervix of the uterus
C)   Liver
D)   Ovaries
E)   PancreasF) A) and D)
G) B) and E)

Question 11

Many tumors secrete their own growth factors.This form of stimulation is called:

Accepted Answer

A)   Autocrine
B)   Heterocrine
C)   Paracrine
D)   Endocrine
E)   ExocrineF) None of the above
G) A) and E)

Question 12

Which of the following physical carcinogens is the cause of most skin cancers in humans?

Accepted Answer

A)   Ultraviolet light
B)   Infrared light
C)   X-rays
D)   Radon
E)   Gamma raysF) B) and D)
G) B) and C) A

Question 13

Tumors composed of malignant glands or ducts are known as:

Accepted Answer

A)   Adenocarcinoma
B)   Carcinoma
C)   Cystadenomas
D)   Liposarcoma
E)   FibrosarcomaF) A) and D)
G) A) and B)

Question 14

Retinoblastoma gene (RB1) is classified as a(n) :

Accepted Answer

A)   Oncogene
B)   Tumor suppressor gene
C)   Point mutation
D)   Gene amplification
E)   Viral oncogene inserted into the human genomeF) None of the above
G) B) and D)

Question 15

Teratomas originate from:

Accepted Answer

A)   Germ cells of the ovary
B)   Brain cells
C)   Thyroid cells
D)   Endocrine cells of the pancreas
E)   Fallopian tubesF) C) and E)
G) C) and D)

Question 16

Carcinoma of the stomach has the highest incidence in:

Accepted Answer

A)   England
B)   Japan
C)   United States
D)   Israel
E)   FranceF) C) and D)
G) A) and E) B

Question 17

The most important source of chemical carcinogens in the human habitat is:

Accepted Answer

A)   Cigarette smoke
B)   Asbestos
C)   Air pollution
D)   Food additives
E)   Pesticides in the foodF) A) and D)
G) A) and C)

Question 18

The most common autosomal dominant disease,which affects more than 3 million Americans,presents with numerous subcutaneous neural sheath tumors and is known as:

Accepted Answer

A)   Neurofibromas
B)   Meningiomas
C)   Neurofibromatosis type I
D)   Neurofibromatosis type II
E)   Wilms' tumorF) D) and E)
G) A) and E)

Question 19

Workers employed in the chemical industry and exposed to high levels of aniline dyes are at increased risk of developing cancer of the:

Accepted Answer

A)   Brain
B)   Lung
C)   Stomach
D)   Urinary bladder
E)   TestisF) A) and C)
G) A) and D)

Question 20

Hodgkin's lymphoma is a neoplasm that typically involves the:

Accepted Answer

A)   Brain
B)   Lungs
C)   Heart
D)   Liver
E)   Lymph nodesF) C) and E)
G) A) and E)

Exam 4: Neoplasia

Which of the following conditions is characterized by a defect of a DNA repair enzyme?

Correct AnswerverifiedShow Answer

Researchers who deal with neoplasia in the human populations and also study the environmental causes of tumors are known as:

Correct AnswerverifiedShow Answer

The most important risk factor(s) for breast and colon cancer is (are) :

Correct AnswerverifiedShow Answer

Alpha-fetoprotein is a tumor marker for malignant tumors originating in the:

Correct AnswerverifiedC

Benign protuberant tumors found on the skin,mouth,or larynx are called:

Correct AnswerverifiedShow Answer

A lung tumor that has spread to the brain has metastasized via:

Correct AnswerverifiedShow Answer

Malignant tumors composed of embryonic cells are often called:

Correct AnswerverifiedShow Answer

The cancer of chimney sweeps identified in the eighteenth century in England was related to a component of tar that is chemically classified as:

Correct AnswerverifiedShow Answer

The incidence of which cancer has been rising in the United States during the past 20 years?

Correct AnswerverifiedShow Answer

Human papillomavirus (HPV) has been implicated in the pathogenesis of carcinoma of the:

Correct AnswerverifiedShow Answer

Many tumors secrete their own growth factors.This form of stimulation is called:

Correct AnswerverifiedShow Answer

Which of the following physical carcinogens is the cause of most skin cancers in humans?

Correct AnswerverifiedA

Tumors composed of malignant glands or ducts are known as:

Correct AnswerverifiedShow Answer

Retinoblastoma gene (RB1) is classified as a(n) :

Correct AnswerverifiedShow Answer

Teratomas originate from:

Correct AnswerverifiedShow Answer

Carcinoma of the stomach has the highest incidence in:

Correct AnswerverifiedB

The most important source of chemical carcinogens in the human habitat is:

Correct AnswerverifiedShow Answer

The most common autosomal dominant disease,which affects more than 3 million Americans,presents with numerous subcutaneous neural sheath tumors and is known as:

Correct AnswerverifiedShow Answer

Workers employed in the chemical industry and exposed to high levels of aniline dyes are at increased risk of developing cancer of the:

Correct AnswerverifiedShow Answer

Hodgkin's lymphoma is a neoplasm that typically involves the:

Correct AnswerverifiedShow Answer

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C

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A

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B

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